
人 淋巴细胞蛋白酶 蛋白, 无标签
产品名称: 人 淋巴细胞蛋白酶 蛋白, 无标签
英文名称: Human Granzyme B Protein, Tag Free
产品编号: GZB-H5213
产品价格: 1840
产品产地: 中国
品牌商标: 北京百普赛斯生物科技股份有限公司
更新时间: 2025-09-19T18:06:11
使用范围: null
规格 | 价格 |
20ug |
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Granzyme B (GZMB) is a cytosolic protease abundant in cytotoxic T-cells and natural killer cells, pivotal for immune defense. Delivered into target cells, GZMB activates caspase-independent pyroptosis by cleaving gasdermin-E (GSDME). This triggers pyroptosis, leading to target cell death. GZMB exhibits substrate specificity for aspartate residue cleavage and contributes to an activation cascade of caspases, impacting apoptosis execution. Involved in bacterial infection response, GZMB cleaves and activates caspase-7, promoting plasma membrane repair. Its multifaceted activities underscore its crucial role in immune responses and cellular defense.